{"id":1158,"date":"2021-03-23T19:36:03","date_gmt":"2021-03-23T19:36:03","guid":{"rendered":"https:\/\/atonco-pharma.com\/technology\/"},"modified":"2022-09-02T19:00:42","modified_gmt":"2022-09-02T19:00:42","slug":"technology","status":"publish","type":"page","link":"https:\/\/atonco-pharma.com\/en\/technology\/","title":{"rendered":"Technology"},"content":{"rendered":"\n[et_pb_section fb_built=”1″ admin_label=”Header” _builder_version=”4.16″ min_height=”100px” custom_width_px__hover=”1080px” custom_width_px__hover_enabled=”1080px” custom_width_percent__hover=”80%” custom_width_percent__hover_enabled=”80%” locked=”off” global_colors_info=”{}” parallax_1__hover=”off” parallax_1__hover_enabled=”off” parallax_2__hover=”off” parallax_2__hover_enabled=”off” parallax_3__hover=”off” parallax_3__hover_enabled=”off” parallax_method_1__hover=”on” parallax_method_1__hover_enabled=”on” parallax_method_2__hover=”on” parallax_method_2__hover_enabled=”on” parallax_method_3__hover=”on” 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Technology<\/h1>[\/et_pb_text][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”19px” custom_padding=”0px||0px|||” global_colors_info=”{}”]

The technology developed by Atonco is a highly promising disruptive innovation in the eradication of residual microscopic disease or isolated or clustered residual tumor cells, rapidly accessible to an astatine-211 labeled radiopharmaceutical.<\/p>[\/et_pb_text][et_pb_image src=”https:\/\/atonco-pharma.com\/wp-content\/uploads\/2021\/06\/laboratory-5.jpg” title_text=”laboratory (5)” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.16″ _module_preset=”default” custom_padding=”0px||0px|||” global_colors_info=”{}”]

The use of alpha-emitting radionuclides is a topical issue and of great medical interest because of the high cytotoxic double stranded DNA break effect of alpha particles on tumor cells due to their high linear energy transfer (LET) and of the recognized good tolerance due to the very short path length of alpha particle allowing to relatively spare normal tissue cells close to tumor cell clusters.<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=”on|off|off” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/atonco-pharma.com\/wp-content\/uploads\/2022\/08\/Atonco-1-english.png” title_text=”Atonco-1-english” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.17.4″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=”on|off|off” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/atonco-pharma.com\/wp-content\/uploads\/2022\/08\/ATONCO-Technologie-ENGL.jpg” title_text=”ATONCO-Technologie-ENGL” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.17.4″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” box_shadow_style=”preset1″ global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]

BIBLIOGRAPHY<\/strong><\/p>\n

\u00a0<\/strong>– Barbet J, Chatal JF. The best radionuclide for radioimmunotherapy of small tumors: beta- or alpha-emitters ? Eur J Nucl Med Mol Imaging 2011;38: 271-273<\/a><\/p>\n

– Chatal JF, Kraeber-Bode\u0301re\u0301 F, Cherel M, Haddad F. Alphatherapy, the new\u00a0 impetus to targeted radionuclide therapy ?. Eur J Nucl Med Mol Imaging 2018;45:1362-1363<\/a><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"

TechnologyThe technology developed by Atonco is a highly promising disruptive innovation in the eradication of residual microscopic disease or isolated or clustered residual tumor cells, rapidly accessible to an astatine-211 labeled radiopharmaceutical.The use of alpha-emitting radionuclides is a topical issue and of great medical interest because of the high cytotoxic double stranded DNA break effect […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1158","page","type-page","status-publish","hentry"],"yoast_head":"\nTechnology: innovation with astatine-211 - Atonco<\/title>\n<meta name=\"description\" content=\"Our technology is a highly promising disruptive innovation of alpha-immunotherapy using astatine-211\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/atonco-pharma.com\/en\/technology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Technology: innovation with astatine-211 - 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